Effect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill

TitleEffect-directed analysis and mixture effects of AhR-active PAHs in crude oil and coastal sediments contaminated by the Hebei Spirit oil spill
Publication TypeJournal Article
Year of Publication2015
AuthorsHong S, Lee S, Choi K, Kim GBeum, Ha SYong, Kwon B-O, Ryu J, Yim UHyuk, Shim WJoon, Jung J, Giesy JP, Khim JSeong
JournalEnvironmental Pollution
Volume199
Pagination110-118
Date PublishedApr
ISBN Number0269-7491
Accession NumberWOS:000351972900015
KeywordsVarious Oil Spills
AbstractThe major AhR-active PAHs were identified in crude oil and oil-contaminated sediments by use of effect-directed analysis. As part of the study, an enhanced potency balance analysis was conducted by establishing the novel relative potency values of (alkyl)-PAHs from the H4IIE-luc bioassay. Silica gel column fractionation of crude oil resulted in greater AhR-mediated potencies in fractions of aromatics (F2) and resins (F3), and such trend was also observed for field collected sediment samples. AhR-mediated potencies of six F2 sub-fractions from HPLC indicated that the majority of F2 responses were attributable to 3-4 ring aromatics. Target PAHs including C4-phenanthrene, C1-chrysene, and C3-chrysene in sediments explained similar to 18% of the bioassay-derived TCDD-EQs, however, the unknown AhR agonists and potential mixture effects remain in question. Overall, the AhR-potency and antagonistic potential of residual oil in sediment tended to decrease over time, thus monitoring of weathering process would be key for the post management of oil-contaminated sites. (C) 2015 Elsevier Ltd. All rights reserved.
DOI10.1016/j.envpol.2015.01.009